Publications

2019

Dargaei Z, Liang X, Serranilla M, Santos J, Woodin MA (2019) Alterations in hippocampal inhibitory synaptic transmission in the R6/2 mouse model of Huntington’s disease. Neuroscience S0306-4522(19)30107-1

2018

Garand D, Mahadevan V, Woodin MA (2018) Ionotropic and metabotropic kainate receptor signaling regulates Cl homeostasis and GABAergic inhibition. Journal of Physiology doi: 10.1113/JP276901.

Dargaei Z, Bang JY, Mahadevan V, Khademullah CS, Bedard S, Parfitt GM, Kim JC, Woodin MA (2018) Restoring GABAergic inhibition rescues memory deficits in a Huntington’s disease mouse model. PNAS 115 (7), E1618-E1626

2017

Maffei A, Charrier C, Caiati M, Barberis A, Mahadevan V, Woodin MA, Tyagaraja (2017) Emerging Mechanisms Underlying Dynamics of GABAergic Synapses. Journal of Neuroscience 37 (45), 10792-10799

Mahadevan V, Khademullah S, Dargaei Z, Pressey JC, Uvarov P, Kwan J, Ackloo S, Bagshaw R,Emili A, Airaksinen MS, Anggono V, DeKoninck Y, Woodin MA (2017) Network organization of native potassium-chloride cotransporter KCC2 interactome revealed by unbiased proteomic anaysis. Under Re-review eLife

Pressey JC, Mahadevan V, Khademullah CS, Chevrier J, Chauhan AK, Meas SJ, Uvarov P, Airaksinen MS, Woodin MA (2017) The Kainate Receptor Subunit GluK2 Promotes Recycling of KCC2 to the Surface Membrane in Hippocampal Neurons. Journal of Biological Chemistry 292(15):6190-6201

2016

Aqrabawi A, Browne C, Dargaei Z, Garand D, Khademullah C, Woodin MA, Kim JC (2016) Top-down modulation of olfactory-guided behaviours by the anterior olfactory nucleus pars medialis and ventral hippocampus. Nature Communications 7: 13721

Quesnel-Vallières M, Dargaei Z, Irimia M, Gonatopoulos-Pournatzis T, Ip J, Sterne-Weiler T, Nakagawa S, Woodin MA, Blencowe BJ, Cordes SP (2016) Misregulation of an activity dependent splicing network as a common mechanism underlying autism spectrum disorders. Molecular Cell 64(6):1023-1034

Raimondo JV, Richards BA, Woodin MA (2016) Neuronal chloride and excitability – the big impact of small changes. Current Opinion in Neurobiology 43:35-42 Mahadevan V, Woodin MA (2016) Regulation of neuronal chloride homeostasis by neuromodulators. The Journal of Physiology 594(10):2593-605

2015

Mahadevan V, Dargaei Z, Ivakine EA, Hartmann AM, Ng D, Chevrier J, Ormond J, Nothwang HG, McInnes RR, Woodin MA (2015) Neto2-null mice have impaired inhibition and are susceptible to seizures. Frontiers in Cellular Neuroscience. 9:368 11 pages

Meyer M, Reimand J, Lan X, Head R, Zhu X, Pressey J, Kushida M, Bayani J, Lionel AC, Clarke I, Cusimano M, Squire J, Scherer SW, Bernstein M, Woodin MA, Bader GD & Dirks P (2015). Single cell derived clonal analysis of human gliobastoma links functional and genomic heterogeneity. PNAS 112(3):851-6.

2014

Nguyen R, Morrissey MD, Mahadevan V, Cajanding J, Woodin MA, Yeomans JS, TakeharaNishiuchi K & Kim J (2014). Parvalbumin and GAD65 Interneuron Inhibition in the Ventral Hippocampus Induces Distinct Behavioral Deficits Relevant to Schizophrenia. The Journal of Neuroscience 34, 14948–14960.

Mahadevan V, Pressey JC, Acton BA, Uvarov P, Huang MY, Chevrier J, Puchalski A, Li CM, Ivakine EA, Airaksinen MS, Delpire E, McInnes RR & Woodin MA (2014). Kainate Receptors Coexist in a Functional Complex with KCC2 and Regulate Chloride Homeostasis in Hippocampal Neurons. Cell Reports 7, 1762–1770.

Richards BA, Xia F, Santoro A, Husse J, Woodin MA, Josselyn SA & Frankland PW (2014). Patterns across multiple memories are identified over time. Nature Neuroscience 17, 981–986. Yiu AP, Mercaldo V, Yan C, Richards B, Rashid AJ, Hsiang H-LL, Pressey J, Mahadevan V, Tran MM, Kushner SA, Woodin MA, Frankland PW & Josselyn SA (2014). Neurons Are Recruited to a Memory Trace Based on Relative Neuronal Excitability Immediately before Training. Neuron 83, 722–735.

2013

Ivakine EA*, Acton BA*, Mahadevan V*, Ormond J, Tang C, Pressey JC, Huang MY, Ng D, Delpire E, Salter MW, Woodin MA†, McInnes RR (†CORRESPONDING AUTHOR) (2013) Neto2 is a KCC2 Interacting Protein Required for Neuronal Cl- Regulation in Hippocampal Neurons. PNAS 110:3561-6.

Takkala P and Woodin MA (2013) Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus. Frontiers in Cellular Neuroscience 7:16.

Vogels TP, Froemke RC, Doyon N, Gilson M, Haas JS, Liu R, Maffei A, Miller P, Wierenga C, Woodin MA, Zenke F, Sprekeler H (2013) Inhibitory Synaptic Plasticity – Spike timing dependence and putative network function. Frontiers in Cellular Neuroscience 7:119.

Ben-Ari Y, Woodin MA, Sernagor E, Cancedda L, Vinay L, Rivera C, Legendre P, Luhmann HJ, Bordey A, Wenner P, Fukuda A, van den Pol A, Gaiarsa JL, Cherubini E (2012) Refuting the challenges of the developmental shift of polarity of GABA actions: GABA more exciting than ever! Frontiers in Cellular Neuroscience 6:35.

Sekeres MJ, Mercaldo V, Richards B, Sargin D, Mahadevan V, Woodin MA, Frankland PW, Josselyn SA (2012) Increasing CRTC1 Function in the Dentate Gyrus During Memory Formation or Reactivation Increases Memory Strength Without Compromising Memory Quality. The Journal of Neuroscience 32(49): 17857-68

Acton BA, Mahadevan V, Mercado A, Uvarov P, Ding Y, Pressey J, Airaksinen MS, Mount DB, Woodin MA (2012) Hyperpolarizing GABAergic Transmission Requires the KCC2 C-Terminal ISO Domain. The Journal of Neuroscience 32(25): 8746-51

2011

Pamenter ME, Hogg DW, Ormond G, Shin DS, Woodin MA, Buck LT (2011) Endogenous GABA(A) and GABA(B) receptor-mediated electrical suppression is critical to neuronal anoxia tolerance. PNAS 108(27):11274-9.

Ormond J, Woodin MA (2011) Disinhibition-mediated LTP in the hippocampus is synapse specific. Frontiers in Cellular Neuroscience 5:17.

2010

Lamsa K, Kullmann D, Woodin MA (2010) Inhibitory Synaptic Plasticity and Spike-Timing Dependent Plasticity. Frontiers in Synaptic Neuroscience 2:8 Balena T, Acton BA, Woodin MA (2010) GABAergic synaptic transmission regulates calcium influx during spike timing dependent plasticity. Frontiers in Synaptic Neuroscience 2:16

2009

Ormond J, Woodin MA (2009) Disinhibition Mediates a Form of Hippocampal Long-Term Potentiation in Area CA1. PLoS ONE 4(9):e7224

2008

Saraga F, Balena T, Wolansky T, Dickson CT, Woodin MA (2008) Inhibitory synaptic plasticity regulates pyramidal neuron spiking in the rodent hippocampus. Neuroscience 155:64-75.

Balena T, Woodin MA (2008) Coincident pre- and postsynaptic activity down-regulates NKCC1 to hyperpolarize ECl during development. European Journal of Neuroscience 27(9):2402-12.

Balena T, Acton BA, Koval D, Woodin MA (2008) Extracellular potassium regulates the chloride reversal potential in cultured hippocampal neurons. Brain Research 1205:12-20.

2007

Fiumelli H, Woodin MA (2007) Role of Activity-Dependent Regulation of Chloride Homeostasis in Development. Current Opinion in Neurobiology 17(1): 1-6.

2006

Cheung U, Moghaddasi M, Hall H, Smith JJB, Buck LT, Woodin MA (2006) Excitatory actions ofGABA mediate severe-hypoxia induced depression of neuronal activity in the pond snail (Lymnaea stagnalis). Journal of Experimental Biology 209 (22):4429-4435.

2005 and prior

Woodin MA, Ganguly K, Poo MM (2003) Coincident pre- and postsynaptic activity modifies GABAergic synapses by postsynaptic changes in Cl- transporter activity. Neuron. 39(5):807-20.

Woodin MA, Munno DW, Syed NI (2002) Trophic factor-induced excitatory synaptogenesis involves postsynaptic modulation of nicotinic acetylcholine receptors. The Journal of Neuroscience 22(2): 505-514.

Munno DWM, Woodin MA, Lukowiak K, Syed NI, Dickenson PS (2000) Different extrinsic trophic factors regulate neurite outgrowth and synapse formation between identified Lymnaea neurons. The Journal of Neurobiology 44(1): 20-30.

Hamakawa T, Woodin MA, Bjorgum M, Painter S, Takasaki M, Lukowiak K, Nagle GT, Syed NI (1999) Excitatory synaptogenesis between identified Lymnaea neurons requires extrinsic trophic factors and is mediated by receptor tyrosine kinases. The Journal of Neuroscience 19(21): 9306-9312.

Woodin MA, Hamakawa T, Takasaki M, Syed NI (1999) Trophic factor-induced plasticity of synaptic connections between identified Lymnaea neurons. Learning and Memory 6(3): 307-316.

Woodin MA, Stephenson R (1998) Circadian rhythms in diving behavior and the ventilatory response to asphyxia in Canvasback ducks. American Journal of Physiology 274: R686-R693.

Stephenson R, Peever JH, Woodin MA, Jarsky TM (1997) Heat loss to water during head immersion in the pekin duck. The Journal of Experimental Biology 278:429-434.

BOOKS AND CHAPTERS

Woodin MA (2013) Electrophysiological Methods for Investigating Inhibitory Synaptic Plasticity.  In: Multidisciplinary Tools for Investigating Synaptic Plasticity (Nguyen P, editor). Humana Press, Springer.

Balena T, Acton B, Woodin MA (2011) Activity-dependent inhibitory synaptic plasticity mediated by chloride regulation. In: Inhibitory Synaptic Plasticity (Maffei A, Woodin MA, eds).  Springer: New York.

Ormond J, Woodin MA (2008) Chloride Homeostasis and Development. In: Binder, M.D, Hirokawa, N, Windhorst, U, (eds). Encyclopedia of Neuroscience. Springer, Berlin,
Heidelberg, New York.

Woodin MA, Poo MM (2003) Activity-dependent regulation of cation-chloride cotransporters. In: Excitatory-inhibitory balance: synapses, circuits and systems plasticity. Ed.: Takao K Hensch.  Kluwer Academic Press.

BOOKS EDITED

Maffei A, Woodin MA. 2011. Inhibitory Synaptic Plasticity. Springer: New York.